inositol trisphosphate

inositol trisphosphate
(= IP3, InsP3)
Inositol 1,4,5 trisphosphate is important as a second messenger. It is released from phosphatidyl inositol bisphosphate by the action of a specific phospholipase C enzyme (PLCg) and binds to and activates a calcium channel in the endoplasmic reticulum.

Dictionary of molecular biology. 2004.

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  • Inositol-trisphosphate 3-kinase — In enzymology, an inositol trisphosphate 3 kinase (EC number|2.7.1.127) is an enzyme that catalyzes the chemical reaction:ATP + 1D myo inositol 1,4,5 trisphosphate ightleftharpoons ADP + 1D myo inositol 1,3,4,5 tetrakisphosphateThus, the two… …   Wikipedia

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  • Inositol — myo Inositol[1] …   Wikipedia

  • Inositol triphosphate — chembox new ImageFile = IP3.png ImageSize = IUPACName = OtherNames = Section1 = Chembox Identifiers Abbreviations = CASNo = 85166 31 0 EINECS = PubChem = 55310 SMILES = InChI = RTECS = MeSHName = ChEBI = KEGG = ATCCode prefix = ATCCode suffix =… …   Wikipedia

  • Inositol triphosphate receptor — protein Name = inositol 1,4,5 triphosphate receptor, type 1 caption = width = HGNCid = 6180 Symbol = ITPR1 AltSymbols = EntrezGene = 3708 OMIM = 147265 RefSeq = NM 002222 UniProt = Q14643 PDB = ECnumber = Chromosome = 3 Arm = p Band = 26.1… …   Wikipedia

  • inositol — 1,2,3,4,5,6 Hexahydroxycyclohexane; a member of the vitamin B complex necessary for growth of yeast and of mice; absence from the diet causes alopecia and dermatitis in mice and “spectacle eyes” in rats. It occurs in a number of stereoisomeric… …   Medical dictionary

  • Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase — In enzymology, a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase (EC number|3.1.3.67) is an enzyme that catalyzes the chemical reaction:phosphatidylinositol 3,4,5 trisphosphate + H2O ightleftharpoons phosphatidylinositol 4,5 bisphosphate + …   Wikipedia

  • Multiple inositol-polyphosphate phosphatase — Identifiers EC number 3.1.3.62 CAS number 116958 30 6 …   Wikipedia

  • Phosphatidylinositol (3,4,5)-trisphosphate — (PtdIns(3,4,5) P 3) commonly abbreviated to PIP3 is the product of the class I phosphoinositide 3 kinases (PI 3 kinases) activity on phosphatidylinositol (4,5) bisphosphate. PtdIns(3,4,5) P 3 is dephophosphorylated by the phosphatase, PTEN on the …   Wikipedia

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